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生物醫學暨檢驗科學雜誌第35卷第2期 Journal of Biomedical & Laboratory Sciences Vol. 35, No. 2, 2023

案例報告 Case Report

臨床上罕見的異體抗體:Anti-Sda Antibody
The Rare Allo-antibody in Clinical Operation: Anti-Sda Antibody
俞孟均,陳定平,張永達,尤慧玲
Meng-Chun Yu, Ding-Ping Chen, Yuan-Ta Chang, Huey-Ling You
生檢雜誌2023;35:84-89 【Abstract】 【摘要】看PDF需登入會員
中文摘要
一名 77 歲男性在輸注減除白血球的紅血球濃厚液 6 單位後,抗體篩檢結果由陰性轉為出現弱陽性,無法鑑定出抗體且交叉試驗為陽性,最後經尿液中和試驗確認抗體為 Anti-Sda Antibody。因該病人 Hemoglobin 及紅血球數目的變化,建議只可使用交叉試驗結果陰性的血品。
關鍵詞:Sda抗體、Sda抗原、輸血、異體抗體、遲發性溶血性輸血反應、SID 血型
Abstract
A 77-year-old male was transfused with 6 units leukocyte-reduced RBCs, then his antibody screen turned to be weak positive. Moreover, it couldn’t be identified by antibody identification, and the cross-match test was incompatible. Finally, the antibody was confirmed anti-Sda by urine neutralization test. Due to the change of his hemoglobin level, we suggest that only the blood products with compatible serological cross-match test can be issued.
Key words:Anti-Sda Antibody, Sda antigen, Transfusion, Allo-antibody, Delayed Hemolytic Transfusion Reaction, SID blood group